James James M. Zavislan

 

 

Associate Professor, Institute of Optics
Associate Professor, Department of Dermatology
Associate Professor, Biomedical Engineering

  

 

 University of Rochester
 Institute of Optics, Wilmot 403

 CPU  270186
 275 Hutchison Rd
 Rochester, NY 14627-0186
             

 

 (585) 275-9819

  zavislan@optics.rochester.edu                      

 

 

General Research Interests

 

Improve the performance of optical imaging systems by modeling and measuring the coherence properties of light returned  from objects of interest and adjacent objects not of interest. Applications for this research include biomedical imaging, material science, and remote sensing. Current projects include improving the performance and specificity of reflectance confocal microscopy in clinical applications.

 

 

Other Interests

 

Clinical Optical Instrumentation, Optical Design, Optical Fabrication, Optical Design using Anisotropic Optical Materials, Tolerancing of Optical Systems, Optical Design for Manufacturing

 

    

Education

 

PhD, The Institute of Optics, University of Rochester, 1988

 

BS, The Institute of Optics, University of Rochester, 1981, High Honors

 

 

Previous Employment

 

May 1 2002-present–Associate Professor, The Institute of Optics, University of Rochester

 

1992 to 2002 - Senior Vice President for Technology / Chief Technical Officer- Lucid, Inc

 

1988 to 1992 - Research Staff Member - IBM Research Division, Almaden Research Center

 

Consulting and Other Activities:

 

 

Professional Organizations, Honors and Awards

 

Member, Optical Society of America

Member, SPIE, The Optical Engineering Society

Member, Institute of Electrical and Electronics Engineers

American National Standards Institute, Z136-Safe Use of Lasers Committee

Bausch and Lomb Science Medal, 1976

University of Rochester, Wilson Scholar, 1978

Tau Beta Pi, 1980

Tau Beta Pi Prize, University of Rochester, 1981

Phi Beta Kappa, 1981

John and Fannie Hertz Fellow, 1982-1987

IBM Research Division Award, Optical System Analysis for Optical Storage, 1992

IBM First and Second Patent Plateau Awards

 

 

Other Professional Activities

 

NIH Review Panel, U54 applications received in response to RFA CA 03-002, Network for Translational Research:  Optical Imaging.

Program Chair, Optical Society of America, Rochester Section, 2002-2003

President-Elect, Optical Society of America, Rochester Section, 2005

Current Member, American National Standards Institute, Z136-Safe Use of Lasers Committee

Chair, Joseph Fraunhofer Award Committe, Optical Society of America

Member, A.E. Conrady Award Committee, 2002-2004, SPIE The International Society for Optical Engineering

Member, Optical Society of America, Engineering Council 1990-1994

Program Co-chair, Optical Society of America, Optical Design for Photonics Topical Meeting,  Palm Springs.

California 1993

Former Vice-Chair, Optical Society of America Optical Fabrication and Testing Technical Group.

Organizing Chair, Optical Society of America, Regional Engineering Workshop, Palo Alto California, 1990

Chair, Local Section of Optical Society of  America, Northern California, Teacher’s Symposium, 1989

 

 

Teaching/Lectureships

 

Optics 197:  Optics Freshman Seminar, University of Rochester, Institute of Optics, (Spring 2004)

Optics 256:  Optics Laboratory, University of Rochester, Institute of Optics, (Spring 2004)

Optics 261:  Interference and Diffraction, University of Rochester, Institute of Optics, (Winter 2001, 2002, 2003)

Optics 242: Aberrations, Interferometry and Optical Testing, University of Rochester, Institute of Optics, (Fall 2001, 2002, 2003)

Optical Engineering for Biomedical Optics, University of Rochester, Institute of Optics, (Modern Optical Engineering Summer School, 2002, 2003)

Optical Engineering Laboratories, University of Rochester, Institute of Optics, (Fundamental of Optics and Modern Optical Engineering Summer School, 2002, 2003)

Engineering Clinics: Ethos of Engineering, University of Rochester, School of
Engineering, 1995-1998

 

 

Products Developed

 

Lucid, Inc.  VivaScope 1000, In-vivo Confocal Microscope, Managed overall microscope design and developed patented optical system for research prototypes and commercial units.  Total production 30 units.

Global Election Systems, Accuvote, Optical Mark Sensor for Elections, Managed overall sensor design and developed patented electro-optic sensor for research prototypes and commercial units.  Sensor is the most widely used optical ballot scanning technology used in the United States.  This sensor was the most accurate (3x more accurate than the next system) voting system in Florida during the 2000 election.  Currently viewed as having the lowest error rate in the country.  Florida commission reviewing the 2000 Presidential Election recommended this technology for all Florida’s election equipment. A Caltech/MIT report recommended upgrading the nation’s voting system with this type of voting system. Total production currently stands at over 15,000 units.  System now called AccuVote-OS and is manufactured and distributed by by Diebold Elections Systems.

Light Source/ X-rite: Colortron I and Colortron II and IIc,  Hand-held spectrophotometer,  Developed patented optics and optomechanics for research prototypes and commercial units.  Winner of the 1995 Graphics Arts Technical Foundation InterTech Award to honor excellence in technology.  Total production 16,000 units.

Chapman Instruments, MP-2000, Precision Surface Profilometer.  Developed research prototype.

 

 

Bibliography

Thesis

 

Prediction and Measurement of Light Scattering from Controllably Rough Optical Interference Coatings, Ph.D. Thesis, Univ. of Rochester, (University Microfilms, Ann Arbor, MI)

 

 

Books

 

Selected Papers on Optical Storage, (editors G.T. Sincerbox and J.M. Zavislan), SPIE Milestone Series, SPIE Optical Engineering Press, Bellingham, 1992.

 

 

Peer-Reviewed Papers

 

"Single molecule orientations determined by direct emission pattern imaging," M. A. Leib, J.M. Zavislan, L. Notvotny, J. Opt. Soc. Am. B, 21 1210-1215 (2004).

"Detectability of contrast agents for confocal reflectance imaging of skin and microcirculation," M. Rajadhyaksha, S. González, J. M. Zavislan, J. Bio. Opt, 9, 323-31. (2004).

"Non Invasive Imaging, Treatment and Microscopic Confirmation of Clearance of Basal Cell Carcinoma," M. Goldgeier, C. M. Alessi, J.M. Zavislan, D. Harris, S. González, Dermatological Surgery 29, 1-6 (2003).

"Confocal Cross-Polarized Imaging of Skin Cancers to Potentially Guide Mohs Micrographic Surgery" M. Rajadhyaksha, G. Menaker, S. González, J. M. Zavislan, P.J. Dwyer, Optics in 2001, Optics and Photonics News, 12 no. 12, pg 30 (2001)

"In Vivo Confocal Scanning Laser Microscopy of Human Skin II: Advances in Instrumentation and Comparison with Histology," M. Rajadhyaksha, S. González, J. M. Zavislan, R.R. Anderson, R.H. Webb, J. Invest. Derm. 113, 293-303 (1999).

"Confocal Reflectance Microscopy of Unstained Tissue In Vivo," M. Rajadhyaksha, J. M. Zavislan, Retinoids 14, 26-30 (1998).

"Angular scattering from optical interference coatings: scalar scattering predictions and measurements," J.M. Zavislan, Appl. Opt. 30, 2224-44 (1991).

 

 

PROCEEDINGS AND OTHER PUBLICATIONS

 

"Confocal Laser Microscope Images Tissue In Vivo," M. Rajadhyaksha, J. M. Zavislan, Laser Focus World, Feb. 1997.

"Clinical real-time confocal imaging of human skin and oral tissues in vivo," Rajadhyaksha, M.; Langley, R.G.B.; Gonzalez, S.; White, M.; Zavislan, J.M.; Webb, R.H.; Anderson, R.R., Conference Proc. LEOS '97, 10th Annual Meeting. IEEE Lasers and Electro-Optics Soc. 1997 Annual Meeting (Cat. No.97CH36057), 299-300 (1997)

"A Constant-Bandwidth Grating-Lens Spectrometer," E.M. Granger, J.M. Zavislan, Proc. of SPIE 2413, 333-341 (1995).

"Effect of track crossing on focus servo signals: feedthrough," M. Latta, T. Strand, J.M. Zavislan, Proc. of SPIE 1663, 157-163 (1992).

"Fabrication of grooved glass substrates by phase mask lithography," P.J. Brock, M. D. Levenson, J.M. Zavislan, J.R. Lylera, J.C. Cheng, C.V. Podlogar, Journal of Vacuum Science & Technology B (Microelectronics Processing and Phenomena) 9, 3155-3161 (1991). Also published in Proc. of SPIE 1463, 87-100 (1991).

"Analytic statistical model of magneto-optic read paths," J.M. Zavislan, Proc. of SPIE 1316, 101-103 (1990).

"Micro and Integrated Optics for Optical Data Storage," J.M. Zavislan, G.T. Sincerbox, B.N. Kurdi, IEEE Proceedings of Systems Design & Networks, Santa Clara, (1989).

"Nonlinear optical studies of polysilanes," P. Shulka, PM.. Cotts, R.D. Miller, S. Ducharme, R. Asthana, J.M. Zavislan, Molecular Crystals and Liquid Crystals 183, 241-259 (1990).

"Nonlinear polysilane thin films," F.M. Schellenberg, R.L. Byer, J. Zavislan, R.D. Miller in Proceedings in Physics: Nonlinear Optics of Organics and Semiconductors, (Springer Verlag, Berlin) p. 192-195, 1989.

"Surface roughness evaluation by image analysis in Nomarski DIC microscopy," M.J. Fairlie, R.S. Timsit, J.M. Zavislan, Proc. Of SPIE 749, 105-113 (1987).

"Optical surface characterization and testing challenge optical fabrication community," J.M. Zavislan, Laser Focus, p. 56-58, September 1985.

"Microprofiling of precision surfaces," J.M. Zavislan, J.M. Eastman, Proc. of SPIE 525, 169-173 (1985)

"A new optical surface microprofiling instrument," J.M. Eastman, J.M. Zavislan, Proc. of SPIE 429, 56-64 (1983)

 

INVITED PRESENTATIONS/SYMPOSIA

 

June 2004, Invited Presentation, "New Opportunities in Ocular Surface Imaging," 49th Annual Ophthalmology Conference, University of Rochester Medical Center, Rochester, New York

June 2003, Invited Briefing, "Economic Development Activities at University of Rochester: Center for Institute Ventures," Upstate Alliance for Innovation, 2003 Retreat, Beaver Hollow, New York

May 2003, Invited Presentation, "Future Directions for Reflectance Confocal Microscopy", Dermatology Department, University of Rochester Medical Center, Rochester, New York

October 2002, Invited Presentation, Confocal Imaging of Unprepared Breast Tissue, Elizabeth Wende Breast Clinic, Rochester, New York

September 2002, Featured Poster, Reflectance Confocal Imaging of Non-histologically Prepared Breast Tissue: Effects of Citric Acid and Glycerin Immersion Liquids, Third Inter-Institute Workshop on Diagnostic Optical Imaging and Spectroscopy: The Clinical Adventure, National Institutes of Health, Bethesda, Maryland

September 2002, Invited Presentation, Real-time In-vivo Pathological Interpretation:
Experience from Dermatology
, Center for Visual Science, University of Rochester, Rochester, NY

August 2002, Featured Presentation, Center for Institute Ventures: A New Model for Fueling Economic Development, Presented to Dr. R. Bessette, Director, New York State Office of Science, Technology and Academic Research, University of Rochester, Rochester, NY

June 2002, Invited Presentation, The Institute of Optics : Exciting Times in Rochester, June 2002, Presented to Senator Clinton and Members of the Confederation of Indian Industry, Rochester Institute of Technology, Rochester NY

June 2002, Invited Presentation, Video-Rate Non-Invasive Imaging:

Real-time pathology for diagnosis and therapy monitoring, Bausch and Lomb Corporate Research, Rochester, NY

June 2002, Invited Presentation, Optical Engineering Considerations when Imaging Living Tissues, Center for Visual Science, University of Rochester, Rochester, NY

June 2002, Invited Presentation, Real-time Pathology Imaging, GE Global Research Center, Niskayuna, NY

November, 2001, Invited Seminar, Clinical Confocal Microscopy: Real-Time Pathologic Interpretation, University of Texas at Austin

June, 2001, Biomedical Product Development: Clinical Confocal Imaging, University of Rochester, Biomedical Engineering Department, Summer Program, Rochester, NY

March 2001, Clinical Studies Presentation, Strong Memorial Hospital Pathology Department, Rochester, NY

March 2001, Invited Presentation, Advances in Dermatology Imaging, Optical Society of America, Rochester Local Section, Rochester, NY

April 2000, Invited Presentation, High-Resolution Near-infrared Confocal Imaging for Clinical Medicine, American Society for Testing and Materials Conference, General Electric Global Research Center, Niskayuna, NY

January 2000, Co-chair, Optical Diagnostics Panel Discussion at Wellman Laboratories Photomedicine 2000 Conference, Wellman Laboaratories of Photomedicine, Department of Dermatology, Harvard Medical School, Boston, NY

January 2000, Invited Presentation Near-Infrared Confocal Imaging for Clinical Medicine, New England Chapter of the Optical Society of America.

April 1999, Invited Presentation, Near-infrared Confocal Imaging for Clinical Medicine, Institute of Optics Industrial Associates Meeting, University of Rochester

February 1999, Invited Symposia, Clinical Confocal Imaging: Applications for telepathology and surgical pathology, United States Institute for Surgical Research, Fort Sam Houston, Texas.

June 1996, Invited Presentation, Developing Precision Electro-Optic Instrumentation for Business and Consumer Markets, Conference of Lasers and Electro-Optics Conference, LEAP program.

 

Inventor or Co-Inventor On 41 US Patents Granted

 

6,745,067 A system for marking the locations of imaged tissue with respect to the surface of the tissue

6,720,547 System and method for enhancing confocal reflectance images of tissue specimens

6,710,875 Imaging system using polarization effects to enhance image quality

6,684,092 System for facilitating pathological examination of a lesion in tissue

6,668,186 Cellular surgery utilizing confocal microscopy

6,577,394 Imaging system using polarization effects to enhance image quality

6,424,852 System for confocal imaging within dermal tissue

6,413,252 Confocal microscope for facilitating cryosurgery of tissue

6,411,434 Cassette for facilitating optical sectioning of a retained tissue specimen

6,330,106 Tissue specimen holder

6,304,373 Imaging system using multi-mode laser illumination to enhance image quality

6,263,233 Confocal imaging through thick dermal tissue

6,194,698 Electro-optical sensor circuitry

6,134,010 Imaging system using polarization effects to enhance image quality

6,134,009 Imaging system using polarization effects to enhance image quality

5,995,867 Cellular surgery utilizing confocal microscopy

5,953,126 Optical profilometry

5,880,832 Spectrophotometry

5,860,967 Dermatological laser treatment system with electronic visualization of the area being treated

5,836,877 System for facilitating pathological examination of a lesion in tissue

5,825,486 Electro-optic module especially suitable for use in a spectrophotometer

5,788,639 Confocal imaging through thick dermal tissue

5,786,585 Optical symbol (bar code) reading systems and devices

5,742,389 Spectrophotometer and electro-optic module especially suitable for use therein

5,714,750 Bar code scanning and reading apparatus and diffractive light collection device suitable for use therein.

5,701,175 Spectrophotometer mouse

5,691,830 Holographic optical system including waveplate and aliasing suppression filter

5,684,582 Spectrophotometry

5,653,706 Dermatological laser treatment system with electronic visualization of the area being treated

5,635,726 Electro-optical sensor for marks on a sheet

5,632,741 Epilation system

5,537,617 Multi-channel optical head and data storage system

5,422,472 Optical symbol (bar code) reading systems having an electro-optic receptor with embedded grating rings

5,416,757 Optical disk drive system for use with disks having different protection layer depths

5,375,138 Optical cavities for lasers

5,353,273 Multi-channel optical head and data storage system

5,253,236 Optical beam focusing and tracking system for an optical disk information storage device

5,247,167 Multiple beam power monitoring system and method with radiation detection and focusing means of overlapping beams

5,202,875 Multiple data surface optical data storage system

5,166,989 Integrated polarization detection system

5,031,993 Detecting polarization state of an optical wavefront

11 Patents Pending